The invention provides an integrated safety evaluation method applied to safety pre evaluation. The method comprises the following steps: (1), using a physical-chemistry-based risk analysis and risk evaluation method; that is, applying a physical-chemistry-based analysis method systematically to carry out a risk analysis and risk evaluation; (2), checking, analyzing, and evaluating whether an engineering project meets the national laws and regulations and standard specifications by using a safety checklist method; (3), carrying out simulated calculation on consequences of possible incidents of fire, explosion, and acute poisoning by applying an accident consequence simulation method, thereby assisting in determining a hazard range and hazard distance; and (4), on the basis of the hazard identification, risk analysis, and risk evaluation results, carrying out analyses comprehensively and providing comprehensive safety protection measures needed to be taken. With the method, a problem of lack of an evaluation method and technology close to the project essence process and system at the safety pre evaluation stage currently can be solved.