The invention discloses an O2O health management method based big data. According to an embodiment of the invention, an online health management plan and an offline health management plan transmitted by a server are obtained via an intelligent terminal for a user to view and execute; in a preset period, a data acquisition terminal acquires information on physical signs of the user based on acquisition rules, and transmits the information on the physical signs to the intelligent terminal; the intelligent terminal obtains feedback information inputted by the user after the execution of the online health management plan and the offline health management plan; and the server adjusts the online health management plan and the offline health management plan based on the information on the physical signals and the feedback information so as to achieve closed-loop management of health conditions of the user. The invention further discloses an O2O health management system based on big data. The embodiment of the invention combines online and offline, the online and offline health management plans can be adjusted in time according to actual executive conditions of a patient, the closed-loop management of the health conditions of the user is achieved and the health management effects are better.