The invention discloses a preparation method of Chinese angelica extract through a microwave and ultrasonic technology. The preparation method comprises the following steps: washing Chinese angelica to remove the impurities, cooling, drying and grinding Chinese angelica; placing the grinded Chinese angelica in an ultrasonic-microwave extractor, carrying out extraction and filtration, condensing the filtrate under a low pressure, carrying out secondary extraction and filtration on the filtration residues; merging the concentrate and the secondary extract, carrying out centrifugal separation, and condensing the supernate. The extraction method is a pure physical method, no solvent is used, the solvent pollution is avoided, and the solvent is saved. The provided method can prominently improve the yield of effectively components, and is carried out at a low temperature, and thus the loss of effective components is avoided.