The invention discloses a rotating disc type multi-station distiller's yeast block pressing machine, which comprises a frame, a revolution driving assembly, a revolution assembly, a pressing assembly, and a feeding assembly. The revolution assembly comprises a rotation disc, a feeding mould box, a setting mould box, a horizontal mould box, a vertical mould box, an integral mould box, and a discharge mould box. The pressing assembly is arranged above the revolution assembly and is composed of a setting press mould, a horizontal press mould, a vertical press mould, an integral press mould, and an extrusion press mould. A distiller's yeast block is moulded by the setting press mould, horizontal gap press mould, vertical gap press mould, and integral press mould for several times, the water and powder in the distiller's yeast block are fully and evenly mixed; the extruded slurry is evenly coated on the whole surface of the distiller's yeast block, the tightness of the distiller's yeast block is proper, the slurry is evenly pasted on the surface, and avoided is the phenomenon that the surface of a distiller's yeast block, which is produced through only one moulding, is tight, the center of the distiller's yeast block is loose, and the slurry is unevenly pasted on the surface. The fermentation effect of the distiller's yeast block is improved, and the distiller's yeast block can be used to produce high-quality liquor.