The invention relates to a method for cutting a plurality of pieces of glass in at least one glass sheet, including the following consecutive steps: a step of automatic generation by a computer having a memory on which programs are capable of calculating a first optimal plane for cutting, by means of a guillotine having a plurality of hierarchical levels (X, Y, Z, V), various pieces in each one of said at least one sheet of glass according to information such as the size of the pieces to be cut; and a step of reading information relating to defects in said at least one sheet of glass, in which the method also includes, subsequently and consecutively: a step of automatic generation by a computer having a memory on which programs are capable of calculating a second optimal plane for cutting, by means of a guillotine having a plurality of hierarchical levels, said at least one sheet of glass, from said first optimal cutting plane and according to at least some of the information relating to the defects including permutations of cutting mistakes from the same hierarchical level within said at least one sheet of glass; and a step of cutting pieces of glass, respecting said second optimum cutting plane generated.