The invention relates to a horseradish tree leaf grain powder brewing packet capable of neutralizing the effect of alcoholic drinks and nourishing faces and a preparation method of the horseradish tree leaf grain powder brewing packet. The horseradish tree leaf grain powder brewing packet is characterized by being prepared from the following raw materials in parts by weight: 15-20 parts of horseradish tree leaves, 200-230 parts of fresh milk, 5-7 parts of radix puerariae powder, 3-5 parts of platycodon roots, 10-15 parts of chili juice, 15-20 parts of sour plums, 20-25 parts of lotus root starch, 15-20 parts of haw vinegar and 20-25 parts of wheat germ powder. The horseradish tree leaf grain powder brewing packet capable of neutralizing the effect of alcoholic drinks and nourishing faces, disclosed by the invention, has the characteristics of being diversified in nutrition, convenient to brew, golden in color, acid, fragrant and palatable in mouth feel and capable of being stored in a drying manner without preservatives. The horseradish tree leaves, the radix puerariae, the platycodon roots and the like are mixed and preserved in the haw vinegar, and the horseradish tree leaves, the radix puerariae, the platycodon roots and the haw vinegar are fully utilized, so that the horseradish tree leaf grain powder brewing packet has the effects of neutralizing the effect of alcoholic drinks, expelling toxin, removing internal heat, stimulating the appetite and the like.