The invention relates to antiseptic and anti-scaling coating of a bionic micro-nano structure. The antiseptic and anti-scaling coating mainly solves the problems that existing anti-scaling coating does not have good durability and cannot tolerate the severe dielectric conditions and technology conditions of oil field three compound combination flooding. The coating comprises A components of 7.5-8.5% of organic silicon resin, 14-16% of epoxy resin, 13-15% of acrylic resin, 13-15% of tetrafluoro resin, 9-11% of copolymer of vinyl chloride and vinyl isobutyl ether, 3.5-4.5% of polyvinyl butyral, 7.5-8.5% of polypropylene glycol diglycidyl ether, 9.5-10.5% of cellulose acetate butyrate liquid, 7-8% of rutile titanium dioxide, 3.5-4.5% of silicon carbide, 5.5-6.5% of glass flake, 0.4-0.6% of antifoaming agent and 0.05-0.1% of accelerator. The coating comprises B components of 4-6% of hydroxyl fluororesin, 2-5% of micron silicon dioxide, 8-10% of nano silica, 0.5-1.5 parts of silane coupling agent, 1-2% of bactericide and 80-85% of diluent. The antiseptic and anti-scaling coating of the bionic micro-nano structure can adapt to the dielectric and technology conditions of three compound combination flooding, and the function of relieving the corroding and scaling phenomena of a three compound combination flooding injection and production system pipeline is achieved.