Disclosed is a mobile phone nano waterproofing film coating machine. The machine comprises a machine platform, an atomizer, a left vacuum chamber, a right vacuum chamber and a mobile phone fixing mold, wherein the atomizer, the left vacuum chamber and the right vacuum chamber are arranged inside the machine platform; the mobile phone fixing mold is arranged between the two vacuum chambers and is used for dividing a mobile phone into two parts and then placing the two parts of the mobile phone in the two vacuum chambers respectively. The left vacuum chamber and the right vacuum chamber are each provided with a mist spray opening and an air suction opening. The number of the atomizer is one, and an outlet of the atomizer is connected with the mist spray openings of the two vacuum chambers through a tee joint and a pneumatic valve. According to the mobile phone nano waterproofing film coating machine, nano waterproofing films are sprayed into the left vacuum chamber and the right vacuum chamber alternately with the help of the pneumatic valve and the tee joint under the condition that the atomizer is shared, and then the other vacuum chamber is vacuumized so that film coating treatment can be conducted on the mobile phone. A motor and a control panel driven by the motor are omitted, and thus the structure is more reasonable and the production cost is lower. Moreover, the pneumatic valve can be opened and closed conveniently and quickly, left-right switching mist spray response time is made shorter, and therefore film coating time is saved.