The invention relates to a technology for removing industrial COD and ammonia nitrogen from monosodium glutamate wastewater. The technology adopts a biological agent for advanced treatment, wherein the biological agent is prepared by mixing aerobic denitrifying bacteria, bacillus, aspergillus niger, rhodococcus, bacillus faecalis alcaligenes, streptomyces lateritius, candida albicans and a sorbent carrier, and comprises various microbes capable of degrading refractory pollutants excellently; the bacteria are matched reasonably, so as to perform excellent degrading effect. Therefore, the technology has a wide application prospect.