The invention discloses a production method for high-purity n-hexane. According to the method, a raw material (8) is rectified and separated in an isohexane removal tower (1), so a tower bottom component (7) of the isohexane removal tower (1) is obtained; the tower bottom component (7) of the isohexane removal tower (1) enters an extracting and rectifying tower (2) and has countercurrent contact with a circulation solvent so as to realize extraction and rectification; a tower top product (9) of the extracting and rectifying tower (2) enters an n-hexane re-evaporation tower (5); a tower top component of the n-hexane re-evaporation tower (5) is high-purity n-hexane (14), and a tower bottom component (11) of the n-hexane re-evaporation tower (5) enters a solvent recovery tower (3); a tower bottom rich solvent (10) of the extracting and rectifying tower (2) enters the solvent recovery tower (3) for solvent recovery; and a tower bottom circulation solvent (13) of the solvent recovery tower (3) returns to the extracting and rectifying tower (2) for cyclic usage. The method has the advantages of high n-hexane purity and low energy consumption.