The invention discloses an experiment device and a method for deep-water jetting, guiding pipe releasing and well drilling. The device comprises a soil box, a pipe column system, a hoisting system, a water supplying and discharging system, a loading system and a measuring system, wherein rock and soil which are used for forming a deep-water jetting seabed environment are arranged in the soil box; the pipe column system is arranged in the soil box; the hoisting system is used for hoisting the pipe column system; the water supplying and discharging system is connected with the soil box and is used for discharging sewage and feeding clear water into the soil box; the loading system is used for applying transverse and vertical load to the pipe column system; the measuring system is connected with the pipe column system and is used for measuring and recording displacement, deformation and stress of the pipe column system during a deep-water jetting process. According to the device disclosed by the invention, a platform is further provided for researching parameters of deep-water jetting and guiding pipe releasing through simulating a deep-water jetting, guiding pipe releasing and well drilling environment and a deep-water jetting, guiding pipe releasing and well drilling operating process.