The invention discloses an intelligent substation and regulation and control center coordinative modeling method, comprising: standardizing the function of a system configuration tool of a substation automatic system; standardizing and expanding device and signal descriptions in an SCD (Substation Configuration Description) file; expanding a measurement model in a CIM/E (Common Information Model/E language) file; making mapping rules of IEC 61850 and IEC 61970 models; by reference to requirements of relay protection information standards and monitor system information standards, performing classified management on the information; automatically exporting the CIM/E file required by a regulation and control center on the side of an intelligent substation by using the system configuration tool, and performing checking; and providing the CIM/E model file for the regulation and control center in an offline or online manner and executing model splicing and storage processing. According to the method, the mapping and conversion from the 61850 model to the 61970 model are finished, the model and information sharing is realized, the model maintenance workload of the regulation and control center is reduced, and the working efficiency is improved.