The invention relates to the field of electric equipment, in particular to a switch cabinet and an operating hole plugging device thereof. The switch cabinet comprises a cabinet body, wherein an operating hole is formed in the cabinet body; a plugging device is arranged on the operating hole; the plugging device comprises a seal door for plugging the operating hole; the seal door is a gate; and a door lock or padlock structure is arranged on the gate. Compared with the prior art, according to the switch cabinet provided by the invention, the seal door is arranged on the operating hole of the cabinet body; a gate form is adopted by the seal door; and the door lock or padlock structure is arranged on the seal door, so that the seal door can be locked through a padlock on the door lock or padlock structure when used; on one hand, a misoperation can be prevented; and on the other hand, the target of reliably plugging the operating hole can be achieved through the gate-type seal door. Therefore, the problem of poor safety caused by poor reliability of the operating hole plugging device in an existing switch cabinet is solved.