The invention discloses a glove for relieving the mouse hand. The glove comprises a glove body, a timer, an electrode, a vibration device, a heating device and a controller, wherein the timer, the electrode, the vibration device, the heating device and the controller are arranged on the glove body, the vibration device comprises a vibrator and a storage battery, and the heating device comprises a temperature sensor and a heating wire. The timer records mouse use time information and transmits the time information to the controller. The controller judges whether the mouse use time information exceeds a preset time threshold value or not; if the mouse use time information exceeds the preset time threshold value, the controller controls the electrode to generate pulses to massage wrist acupuncture points and controls the vibrator according to the pulses generated by the electrode to vibrate to massage the hand back, and the storage battery provides energy required by vibration of the vibrator. The temperature sensor detects temperature information in the glove body, and the heating wire heats the glove body under the control of the controller. The invention further discloses a method for relieving the mouse hand. By means of the glove and method, the effects of completely relaxing the muscle and the joints of the hand of a user, being resistant to coldness and keeping warmth can be achieved, and the occurrence rate of the mouse hand is reduced.