The invention relates to the disperse dye technology field, and provides an environmentally-friendly blue disperse dye mixture and applications in order to adapt the environmental protection trend and meet demands of textiles to disperse blue dyes with excellent performances. The dye mixture is prepared from a dye A and a dye B through mixing. The weight percentage of the dye A in the dye mixture is 60-95%, and the weight percentage of the dye B in the dye mixture is 5-40%. The blue disperse dye with a low cost, a high intensity and high fastness is provided, demands of high-end users home and abroad are met, and environmental protection requirements are met.