An airlift photocatalytic membrane separation coupling reactor for processing organic wastewater comprises an airlift circumfluent photocatalytic reactor; multiple guide cylinders are co-axially arranged in the reactor; a circular zone for lifting/descending fluids is formed between neighbored guide cylinders; the cylinder body of one of the guide cylinders is composed of an inner cylinder wall and an outer cylinder wall, a cavity is formed between the inner cylinder wall and the outer cylinder wall, the upper ends and lower ends of the inner cylinder wall and outer cylinder wall are hermetically connected respectively; the external cylinder wall of the guide cylinder is wrapped by a filter membrane, which is used to separate solid photo catalyst from processed wastewater; the area, which is wrapped by the filter membrane, of the external cylinder wall is provided with a plurality of water-penetrating holes, the upper end of the guide cylinder body is provided with a water collecting pipe that is communicated with the cavity, and the water collecting pipe is connected to an output-backwashing system, which is arranged out of the reactor. In the provided airlift circumfluent photocatalytic reactor, the wastewater and solid photo catalyst can be separated after reactions.