The invention discloses an energy storage system based active load multi-target coordination control method. The multi-target comprises regional power grid call wire power sums, user economical benefits and electric power company operation benefits; the weights of operating targets are adjusted by users according to actual needs; by analyzing power supply output in a demand side, the charging state of the energy storage system, user energy-use needs and real-time electricity price, the real-time output of the energy storage system is automatically planned to realize the most optimized multi-target operating overall result. The control steps comprises: data collecting; parameters setting; data screening; step-by-step optimizing; and instruction executing. The control method can give consideration to both of the user benefits and the electric power company benefits, and dramatically improves the economic benefit and the social benefit of the intelligent demand side, and meanwhile, the policy can be used in energy storage capacity planning and investment of the intelligent demand side in the initial period of construction so as to obtain the highest input/output ratio.