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发明公开
CN105153017A 一种1,4-二氢吡啶衍生物的微波合成方法 无效 - 驳回

一种1,4-二氢吡啶衍生物的微波合成方法
摘要：
本发明公开了一种1,4-二氢吡啶衍生物的微波合成方法采用微波辐射的方法利用芳香醛、乙酰乙酸乙酯和醋酸铵三种反应物合成所需衍生物，与现有技术相比，反应操作方便、反应条件温和，反应时间迅速、对环境污染小的优点，是一种环境友好型催化剂，有效降低了反应时间从而提高了生产效率，降低了生产成本另一方面可以大量用于工业生产，降低反应附加产物对环境的污染危害。
摘要（英）：

The invention discloses a microwave synthesis method of a 1,4-dihydropyridine derivative. The microwave synthesis method has the beneficial effects that the required derivative is synthesized by utilizing the following three reactants by adopting a microwave radiation method: aromatic aldehyde, ethyl acetoacetate and ammonium acetate; compared with the prior art, the microwave synthesis method has the advantages of convenience in reaction operation, mild reaction conditions, high reaction time and low environmental pollution; the 1,4-dihydropyridine derivative is an environment-friendly catalyst; the reaction time is effectively reduced, thus improving the work efficiency and reducing the production cost; on the other hand, the 1,4-dihydropyridine derivative can be used in industrial production in quantity, thus reducing the environmental pollution hazards caused by reaction addition products.

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