The invention discloses a plateau earthquake climatic environment simulating device and belongs to the technical field of testing equipment. The plateau earthquake climatic environment simulating device comprises a plateau earthquake simulating cabin equipped with two cabin layers and an earthquake simulating structure disposed in the plateau earthquake simulating cabin. The top cabin layer of the plateau earthquake simulating cabin is a plateau earthquake chamber and the bottom cabin layer of the plateau earthquake simulating cabin is an earthquake falling chamber. An air supply system, a spraying system, a temperature control system, a sunlight generator, an ice-making system, a mist-making system, and a noise system are disposed in the plateau earthquake simulating cabin. By means of the plateau earthquake simulating cabin and the earthquake simulating structure, the plateau earthquake climatic environment simulating device may simultaneously simulate a plateau, an earthquake, and various extreme climate environments formed by combining the plateau with the earthquake, enables a proofer to experience various plateau and earthquake extreme climates at one time, and solves a problem that a product in the prior art may just simulate a single climate so as to be high in experience cost and manufacture cost.