The invention discloses a comprehensive prevention method for mulberry field insect pests. The method is used for comprehensive prevention by combining a chemical prevention method and a physical prevention method. According to the chemical prevention method, a mixture containing methomyl EC, dichlorvos malathion, imidacloprid wettable powder, propargite emulsifiable concentrate and propoxur wettable powder is evenly mixed and then sprayed on a whole mulberry tree. According to the physical prevention method, yellow boards and blue boards are hung at the top end of the mulberry tree, and insect-killing lamps are installed in a mulberry field; before the mulberry tree is provided for silkworms to eat, comprehensive prevention needs to be conducted firstly. The comprehensive prevention method optimizes combinations and use amounts of the insecticides, so that chemical prevention and physical prevention are organically unified, various pests are prevented through one method, the effect is remarkable, and safety is high. Besides, the comprehensive prevention method enriches main pest research methods of mulberry trees, new reference is provided for field prevention, and insecticide resistance development is slowed down.