The invention discloses a method for performing EBM metal 3D printing on a personalized human body thighbone prosthesis sleeve. The method includes the steps that encrypted CT scanning is performed on the upper middle section of a metaphysis prosthesis part, and CTdicom data are input into Mimics software to reconstruct a grid model; surface reconstruction and smoothing processing are performed on the grid model; post-modification is performed on the bone three-dimensional grid model based on the joint prosthesis design concept; a personalized joint prosthesis three-dimensional model is generated through surface reconstruction and designing; the shape of a personalized joint prosthesis is adjusted through finite element analysis; the three-dimensional model of the implant is input into a rapid prototyping machine and printed through EBM RP technology metal 3D printing. The shape of the printed and manufactured finished product can be completely matched with that of the medullary cavity of the distal femoral metaphysic of every patient, the personalized thighbone prosthesis can be knocked to be implanted just through a few intra-operative medullary cavity files, and good initial fixation and long-time biological fixation can be achieved.