The invention relates to a novel on-load voltage regulation switch of a transformer. The on-load voltage regulation switch comprises a selector switch circuit, wherein the selector switch circuit comprises singular numbers of tapping point switching circuits and odd numbers of tapping point switching circuits, which are symmetrically distributed, wherein the tapping point switching circuits comprise work contacts, transitional contacts and moving contacts which are in contact with the work contacts and the transitional contacts. The on-load voltage regulation switch is characterized in that the tapping point switching circuits comprise work contact control circuits and transitional contact control circuits drawn out from tapping points; the work contact control circuits are input end of a trigger transmitter, which is connected to the work contacts, and the output end of the trigger transmitter is connected with the transitional contact control circuits; the transitional contact control circuits are transitional resistors and are connected with the two ends of a series branch of an overcurrent protection device and a high-voltage thyristor. The on-load voltage regulation switch is simple in structure, low in price and high in reliability, can realize non-electric-arc work and double-state work in the switching process, and has broad application prospect and promotional value.