The invention discloses an anti-frost and high-yield cultivation method for winter potatoes. The cultivation method is characterized by comprising following steps: choosing high-quality seed potatoes to sow and plant; flattening the bed surface after timely fertilizing land and applying pesticide; then laying black film after setting up a micro-spraying hose on the bed surface; then placing fine soil on the black film; in furrows, at least every four rows, installing an anti-frost spraying belt made of a PE high-strength composite flexible tape. The beneficial effects are: on the basis of micro spraying under plastic film and integrated management of irrigation and fertilization, anti-frost spraying belts made of PE high-strength composite flexible tapes are installed on farmland main pipelines; in the event of frost in the morning, a controllable switch of the micro-spraying hoses is turned off, a controllable switch of the anti-frost spraying belts is turned on, and frost is washed off by spraying water for a certain time, so that potato plants are well protected from frost damage. For seed potatoes harvested by use of the cultivation method, the rate of marketable potatoes reaches 91.2%; the anti-frost rate reaches 90% and above; the yield is increased by 453.7kg per Mu and above; production value is increased by 680.5 Yuan per Mu and above; net income is increased by 520.5 Yuan per Mu and above. The cultivation method plays a real role in high and stable yield; and by use of the cultivation method, industrial competitiveness of winter potatoes in south China is increased.