The invention provides a bottle special for dispelling the effect of wine and a using method thereof and belongs to the technical field of beverages. The technical problem of the prior art that time for dispelling the effect of wine is solved. The bottle comprises a cylindrical bottle body with the upper end open, wherein a plurality of disc-shaped trays are arranged in the bottle body at intervals, each tray is provided with a discharging outlet and an overflow port capable of allowing liquid in the tray to overflow, the projected areas, in the vertical direction, of the overflow ports of every two adjacent trays do not coincide, and the projected areas, in the vertical direction, of the discharging outlets of all the trays coincide; a piston mechanism capable of blocking or opening the discharging outlets of all the trays is also arranged in the bottle body, and an opening and closing mechanism capable of allowing liquid in the bottle body to flow out is arranged on the bottom of the bottle body and located on the outer wall of the bottle body. By the adoption of the bottle, the contact area between wine and oxygen in air is increased greatly, so that time for dispelling the effect of wine is effectively shortened, and then people can drink wine more quickly.