The invention discloses a micro-ecological compound preparation with an immunological enhancement function. The compound preparation is prepared from the following raw materials, by weight, 1-3 parts of lactococus lactis powder, 30-50 parts of isomaltose hypgather, 10-15 parts of yeast trace elements, 10-20 parts of NSP enzyme, 8-12 parts of radix astragali polysaccharide and 15-25 parts of fermented wheat bran/soybean meal. The fermented wheat bran/soybean meal is prepared from wheat bran and soybean meal through combined fermentation of lactobacillus plantarum and pediococcus pentosaceus. The mass ratio of wheat bran to soybean meal used for fermentation is 4:1. The yeast trace elements are a mixture of yeast chromium and yeast iron according to a mass ratio of (5-7): (5-7). The micro-ecological compound preparation can enhance organism cellular immunity, humoral immunity and mucosal immunity functions, and has obvious promotion effects on non-specific immune and specific immune response.