The invention belongs to the field of traditional Chinese medicine and particularly relates to a method for measuring the content of main active ingredients in xiaoshuan tongluo tablets. According to the measurement method, the content of ginsenoside Rg1, ginsenoside Rb1 and notoginsenoside R1 in the xiaoshuan tongluo tablets can be measured simultaneously with an HPLC (high performance liquid chromatography) method, a reference substance mixed solution I and a test solution I are injected into a liquid chromatograph respectively according to chromatographic conditions, the injection volume of the reference substance mixed solution I is 10 mu L, the injection volume of the test solution I is 5 mu L, the chromatographic peak area is recorded, and the content is calculated with an external standard method. Meanwhile, according to the measurement method, the content of astragaloside is measured with an ELSD (evaporative light-scattering detector) method, a reference substance mixed solution II and a test solution II are injected into the liquid chromatograph respectively according to chromatographic conditions, the injection volumes of the reference substance mixed solution II are 5 mu L and 10 mu L respectively, the injection volume of the test solution II is 10-20 mu L, the chromatographic peak area is recorded, and the content is calculated according to a two-point external standard method logarithmic equation.