The invention relates to a multi-LED display module management method, which can be applied to an LED display screen system comprising a receiving card and cascaded multiple LED display modules. The multi-LED display module management method comprises a step of wire arrangement detection and a step of point detection. According to the step of wire arrangement detection, multiple signal lines serve as the current external interrupt source one by one by using a timer to realize wire arrangement detection. According to the step of point detection, a timer capture mode or an external interrupt mode is used for reading level values of RGB data lines in the multiple signal lines to obtain point detection result data and store the data. Through carrying out program design on a microprocessor module of each LED display module, intelligent management on the LED display module is realized, and by using serial port communication, wire arrangement detection is thus realized, and even multiple functions such as point detection, IAP functions, working temperature recording, working voltage recording, flash memory management, and authorization management can be realized.