The invention discloses a fireproof and aging resistant locomotive cable, which includes a conductor. An isolation layer covers the outside of the conductor. An insulating layer covers the outside of the isolation layer. A shielding layer covers the outside of the insulating layer. A sheath layer covers the outside of the shielding layer. The sheath layer is made of modified chlorosulfonated polyethylene. Raw materials of the modified chlorosulfonated polyethylene include: chloroprene rubber, chlorosulfonated polyethylene, acrylic rubber, zinc oxide, magnesium oxide, aliphatic acid, tetramethyl-thiuram disulfide, carbon black, kaolin, microencapsulated red phosphorus, a carbon nano tube, a nano silica, a three-layer composite inorganic material, phenyl trimethoxy silane, polyethylene wax, epoxy soybean oil, eleaostearic acid, dicapryl phthalate, dioctyl sebacate, an antioxidant, and phosphite ester. The fireproof and aging resistant locomotive cable has good mechanical properties, good fireproof performance and good aging resistant performance.