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发明公开
CN105288752A 磁性纳米复合生物界面材料及其制备方法 无效 - 驳回

磁性纳米复合生物界面材料及其制备方法
摘要：
本发明公开了一种磁性纳米复合生物界面材料及其制备方法，要解决的技术问题是具有坚强的内固定，促进移植肌腱愈合。本发明由以下质量百分比的材料组成:19.8％Nano-HA，78.7％PLLA-[ASP-PEG]，0.5％多肽，1％γ-Fe2O3。本发明的制备方法，包括固定多肽,制备磁性纳米复合生物界面材料。本发明与现有技术相比，经实验证实细胞复合前后生长、增殖、分化良好,细胞复合Nano-HA/PLLA-[ASP-PEG]/γ-Fe2O3生物界面材料扫描电镜见细胞贴附生长良好,Nano-HA/PLLA-[ASP-PEG]/γ-Fe2O3生物界面螺钉可作为肌腱移植的内固定材料并促进腱骨愈合。
摘要（英）：

The invention discloses a magnetic nanometer compound biological interface material and a preparation method thereof. In order to solve the technical problems, strong internal fixation is achieved, and the healing of transplanted tendons is promoted. The magnetic nanometer compound biological interface material is prepared from, by mass, 19.8% of Nano-HA, 78.7% of PLLA-[ASP-PEG], 0.5% of polypeptide and 1% of gamma-Fe2O3. The preparation method includes the steps of fixing polypeptide and preparing the magnetic nanometer compound biological interface material. Compared with the prior art, it is proved through experiments that growth, reproduction and differentiation of cells are good before and after compounding, a cell compounding Nano-HA/PLLA-[ASP-PEG]/gamma-Fe2O3 biological interface material scanning electron microscope is good in cell adhesion and growth, a Nano-HA/PLLA-[ASP-PEG]/gamma-Fe2O3 biological interface screw can be used as a tendon transplantation internal fixing material and used for promoting healing of tendon bones.

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