The invention provides a protection circuit used for a liquid crystal display. The liquid crystal display comprises a power management chip and load connected with the power management chip. The power management chip provides driving voltage to the load. The protection circuit is connected between the power management chip and the load. The protection circuit also comprises a control module which is used for detecting output current of the power management chip and closing the power management chip when the output current exceeds the preset current threshold. The invention also provides the liquid crystal display with the protection circuit. The protection circuit has an over-current protection function and can effectively protect the liquid crystal display against damage caused by excessive current.