The invention discloses a QoE (Quality of Experience) driven HTTP streaming media on demand buffer region control method. The QoE driven HTTP streaming media on demand buffer area control method comprises the steps of, in a video-on-demand process, by a server, transcoding and packaging video data into multiple streaming media at different quality levels and performing slice storage for the streaming media; by a client, performing reasonable reservation for data in a buffer area of the client based on a real-time network available bandwidth and in consideration of sensitivity of a user for video playing unsmoothness by using a sectional optimization method; and if the data of the buffer area of the client cannot be reserved reasonably, applying for streaming media at the quality level adaptive to the real-time network available bandwidth by utilizing an adaptive optimization algorithm by the client so as to prevent underflow of the data of the buffer area. According to the invention, the QoE driven HTTP streaming media on demand buffer area control method is realized.