The invention relates to a no-load current measurement device of a large-size power transformer. The no-load current measurement device is characterized by comprising a micro-control module, wherein the micro-control module is connected with a data acquisition module and a current sensor in sequence, so that a current signal is acquired; and the micro-control module is connected with a wireless radio frequency module and a GPS (Global Position System) module. The invention further provides the no-load current measurement device of the large-size power transformer. The device can be used for measuring no-load current of the large-size power transformer and provides evidences for grasping the state of the transformer.