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Invention Publication
CN105348386A 抗口蹄疫O型（O/GX/09-7）病毒的单克隆抗体组合及检测该病毒的ELISA试剂盒、金标纸层析试纸 有权 转让

抗口蹄疫O型（O/GX/09-7）病毒的单克隆抗体组合及检测该病毒的ELISA试剂盒、金标纸层析试纸
Abstract:
本发明公开了检测口蹄疫O型(O/GX/09-7)病毒的单克隆抗体组合、ELISA试剂盒及金标纸层析试纸，该组合包括特异性单克隆抗体6D6anti和非特异性单克隆抗体2H10anti，在ELISA检测中以6D6anti作为包被抗体、以2H10anti作为酶标抗体，在胶体金试纸条中以6D6anti作为标记抗体，以2H10anti作为包被抗体可用于检测口蹄疫O型(O/GX/09-7)病毒，并具有高特异性、高灵敏度的优点，本发明将在口蹄疫O型(O/GX/09-7)病毒的检测、疫苗生产、流行病学研究中发挥作用。
Abstract(English):

The invention discloses an a monoclonal antibody combination, an ELISA kit and a gold-labelled paper chromatography test paper for detection of foot-and-mouth disease type O (O/GX/09-7) virus. The combination comprises a specific monoclonal antibody 6D6anti and a non-specific monoclonal antibody 2H10anti. In ELISA detection, the 6D6anti is used as a coating antibody, the 2H10anti is adopted as the enzyme labeled antibody, and in a colloidal gold test strip, the 6D6anti is used as the labeling antibody and the 2H10anti is used as the coating antibody for detection of the foot-and-mouth disease type O (O/GX/09-7) virus. The monoclonal antibody combination has the advantages of high specificity and high sensitivity. The monoclonal antibody combination, the ELISA kit and the gold-labelled paper chromatography test paper provided by the invention can play a role in foot-and-mouth disease type O (O/GX/09-7) virus detection, vaccine production and epidemiologic study.

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