The invention discloses a dynamic matrix control method for a networked system having time delay and packet loss, comprising steps of choosing updated controlled quantity according to a time delay sequence when the time delay, pack loss and disturbed sequence exist in the same time, obtaining step response coefficients under various time delay through analyzing the time delay and combining with a controlled object model, and designing a controller based on a dynamic matrix control algorithm. The invention provides the dynamic matrix control method for the networked system which can effectively solve the time delay, the pack loss and the disturbed sequence.