The invention discloses a wall fixation and adjustment device for a mobile phone. The device comprises a slide rail, a carriage and a mobile phone clamp, the slide rail is of a recess structure, the slide rail is fixed to the wall via bolts, an open end of the slide rail is folded backwardly with the end portion downward, the carriage of an arched structure wraps the open end of the slide rail, the two ends of the carriage are elastically fixed between the end portion of the slide rail and the slide rail, the mobile phone clamp is arranged over the carriage, and the carrier slides on the slide rail during work. According to the device, fixation is firm, the mobile phone can be adjusted in both the horizontal and the vertical directions conveniently, and use is simple and convenient.