The invention relates to the field of lost foam casting and discloses a hole filling material and a production method of castings with eyeholes. The hole filling material contains different grades of fireproof materials with the particle sizes of 0-4 mm, and with the total weight of the fireproof materials as the standard, the fireproof materials with the particle size larger than 0 but smaller than or equal to 0.5 mm account for 25%-35%, the fireproof materials with the particle size larger than 0.5 mm but smaller than or equal to 1 mm account for 15%-25%, the fireproof materials with the particle size larger than 1 mm but smaller than or equal to 2 mm account for 20%-30%, and the fireproof materials with the particle size larger than 2 mm but smaller than or equal to 4 mm account for 20%-30%. By means of the hole filling material, the problem of mechanical sand burning of the eyeholes of the large thick-walled castings can be effectively solved.