The invention discloses a face contact-type self-adaptive undamaged fast installing and fastening device. The device comprises an off-center cylinder, two off-center wedge keys and anti-loose screws; the off-center cylinder is of an annular structure, a section of arc-shaped face is machined on the inner circumference face of the two ends of the annular structure, the arc-shaped face is located on an off-center hole, and the included angle between the off-center hole and a center axis of the annular structure is 8 degrees; threaded holes are formed in the two end faces of the off-center cylinder; the off-center wedge keys comprise wedge-shaped parts and connecting wings, each wedge-shaped part is of a structure that the inner space of the off-center cylinder is matched with the space formed by a tightened shaft or a tightened pipe, the thickness of each wedge-shaped part is larger than that of the space, and threaded holes corresponding to the positions of the threaded holes in the off-center cylinder are formed in the connecting wings. According to the face contact-type self-adaptive undamaged fast installing and fastening device, the requirements that high-reliable and long-lifetime fastening is conducted under high pressure, high temperature, high corrosion, impact, vibration and other complex working condition and in the extremely confined space can be met.