The invention discloses a telescoping mechanism with a manual interface. The telescoping mechanism includes a housing, a motor reducing gear arranged in the housing, a lead screw connected with a motor reducing gear output end, a push rod connected with the lead screw, and a manual rod connected with the push rod, the lead screw is sleeved in the push rod and the lead screw and the push rod are concentrically arranged, the push rod and the lead screw are connected through threads, and the push rod is connected through a sliding block and a sliding groove mechanism with a first gear that is sleeved outside the push rod; and the manual rod is movably connected to the housing and is parallel to the push rod, an output end of the manual rod is connected with a second gear, the second gear meshes with the first gear, a unidirectional control switch is arranged on the manual rod, and unidirectional control of the rotation of the second gear by the manual rod is realized through the unidirectional control switch.