The invention relates to a shoe sole, and provides a bionic kangaroo running shoe sole which can effectively prevent the feet from being injured and has the excellent damping and boosting effects. The bionic kangaroo running shoe sole comprises a shoe sole body, the shoe sole body is provided with a hollow structure which divides the shoe sole body into an upper shoe sole portion and a lower shoe sole portion, the portions, located on the two sides of the hollow structure, of the shoe sole body are each provided with S-shaped damping connection parts used for connecting the upper shoe sole portion with the lower shoe sole portion, and the curvature radius of the upper curve portion of each S-shaped damping connection part is larger than that of the lower curve portion of the S-shaped damping connection part; the upper curve portions cover the side wall of the upper shoe sole portion, and the lower curve portions cover the side wall of the lower shoe sole portion.