The present invention relates to display technology field and particularly to a touch screen and a method of manufacturing the same, a display panel and a display device. The touch screen includes an insulating layer and a touch-controlling electrode. The insulating layer is provided with at least one recess structure in a side thereof and the touch-controlling electrode is arranged in the recess structure, a cross section area of the touch-controlling electrode in a direction perpendicular to a touch face of the touch screen being larger at a position corresponding to the top of the at least one recess structure than at a position corresponding to the bottom of the at least one recess structure. The touch screen eliminates adverse influence of the pattern of touch-controlling electrode on the display while ensuring the touch-controlling effect.