The invention relates to the field of potted plants, in particular to a potted plant in combination with sakura and cherries and a manufacturing method thereof. The manufacturing method comprises the following steps: taking a cherry tree as rootstock; grafting other sakura and the rest types of cherries; and separating grafted parts from a seed tree by a mound layering method to obtain the potted plant. By adopting the method which is simple, easy to operate and low in cost, the potted plant in combination with flowers and fruits is provided.