The invention provides a blackleg control method for flue-cured tobacco. The method comprises the steps of carrying out soil disinfection, carrying out seedling-restitution stage treatment and carrying out vigorously-growing stage management. The seedling-restitution stage treatment means after tobacco seedlings are subjected to transplanting and fix planting, scattering a circle of medicinal powder around each tobacco plant, and covering the medicinal powder with soil, wherein the distance between the medicinal powder and the root of each tobacco plant is 10-15cm, and the dosage of the medicinal powder for each tobacco seedling is 5-7g. The adopted medicinal powder contains the following ingredients in parts by weight: 1-1.5 parts of water, 9-11 parts of sweet potato flour, 2-5 parts of tapioca flour, 2-5 parts of pomegranate peel powder, 3.5-4 parts of xanthium sibiricum powder, 3-7 parts of amber powder, 2.2-2.8 parts of garlic oil, 0.8-1.2 parts of perilla frutescens oil and 1-1.5 parts of gardenia flower extract. The soil disinfection means sprinkling disinfectant powder at the application rate of 65-80kg per mu. By adopting the method provided by invention, the control effect on flue-cured tobacco blackleg is obvious.