The invention provides a foundation pit anti-seepage and settlement control method based on a stereoscopic curtain-well group system. The system is composed of vertical curtains of unequal depths, a horizontal curtain grid and a precipitation well group in a foundation pit. The horizontal curtain grid structure is established based on traditional vertical curtains of unequal depths, and a limited water blocking body in an underground space is formed; by reasonably optimizing the well group structure, and the head loss during underground water movement is increased by sufficiently utilizing the curtain energy consumption theory, so that the purpose of decreasing the drawdown of underground water outside the foundation pit and accordingly decreasing the settlement amount is achieved. According to the stereoscopic curtain-well group system, the wall-well functional mechanism is utilized sufficiently, the problem of instability of the foundation pit caused by seepage can be effectively solved, and foundation pit dewatering is controlled so that ground settlement amount can be prevented; meanwhile, compared with horizontal totally-closed curtains, the project amount and project cost are greatly reduced, and great social benefits and economic benefits are achieved.