The invention discloses a touch screen, a touch display device and a touch screen manufacturing method and aims at improving the positioning accuracy of the touch screen. The touch screen comprises a substrate, multiple first optical devices, multiple second optical devices, a line light source, a third optical device, multiple first light receiving devices and multiple second light receiving devices, wherein the multiple first optical devices and the multiple first light receiving devices are respectively opposite in position and are respectively arranged in the opposite first side region and second side region of the substrate, and the multiple second optical devices and the multiple second light receiving devices are respectively opposite in position and are respectively arranged in the opposite third side region and fourth side region of the substrate. The line light source is located at the intersection position of the first side region and the fourth side region, and the third optical device is located at the intersection position of the first side region and the third side region. The touch screen further comprises a control device for determining positional information of touch points according to light receiving results of the first light receiving devices and the second light receiving devices.