The invention provides an electricity charge calculating system based on multiple settlement main bodies. The system comprises an electric quantity acquisition unit, an operation data acquisition unit, and an electric quantity settlement unit mutually connected in a communication manner, the electric quantity acquisition unit comprises a metering chip and a communication chip, an input terminal of the metering chip is connected with output terminals of a plurality of electric energy meters, and the metering chip comprises a pulse output unit, a digital signal processing unit, a checking error processing unit, and a communication port used for loading electric quantity data. The invention provides an electricity charge settlement method based on multiple settlement main bodies, and electric quantity and electricity price can be rapidly and accurately settled according to multiple settlement main bodies. According to the system and the method, an electric energy settlement platform is established, an integrated calculating platform is provided for generating settlement of power plants and settlement of tie lines between provincial networks, and unified support and parallel processing for the settlement of the whole network are realized.