The invention discloses a hollow locking external fixation stent and a bone fracture fixing device. The hollow locking external fixation stent comprises a tubular stent body and multiple cores arranged inside an inner cavity of the stent body in a sliding mode, multiple hole sets are formed in the length direction of the tube wall of the stent body, each hole set comprises a pair of threaded through holes formed oppositely and a pair of oblong through holes formed oppositely, and the threaded through holes and the oblong through holes are alternately arrayed in a spaced mode; an auxiliary threaded through hole is formed in each core and corresponds to one threaded through hole or one oblong through hole in position. The hollow locking external fixation stent is arranged outside the muscles of a human body and connected with a bone suffering bone fracture through bone nails so that the bone can be fixed to the stent, and then the distance between two sections of bones is adjusted through a threaded rod and nut adjusting device so that the bone fracture portions can be tightly attached; after the bone fracture is cured, it is unnecessary to take out the stent through a secondary operation, so that the pain and economic burden of a patient are reduced.