The invention provides a high-power LED package structure, which comprises a lens (1), a frame (2), a copper substrate (3), a positive connection terminal (6), a negative connection terminal (7), a fan device (4) and a heat sink device (5), wherein the lens (1) is in a hollow hemispherical body and is made of a transparent material; the frame (2) is provided with a plane mirror (21) and a silica gel layer (22); the copper substrate (3) is provided with a first through hole (31), a first fixed block (32), a silver coating (33), a second through hole (34), a third through hole (35) and an LED luminous chip; the fan device (4) comprises a fan (41), a pipeline (42), a first filter net (43) and a second filter net (44); and the heat sink device (5) comprises a heat sink frame (51), a fourth through hole (52), a water pipe (53), a first bracket (54) and a second bracket (55). A high-power LED lamp can be adopted; concern about a cooling temperature is avoided; and the cooling effect is good.