The invention provides an MVR and ME combined heat and power generation salt production system. The system comprises a high pressure boiler, an MVR salt production module, an electric generating set and an ME salt production module, the high pressure boiler, the MVR salt production module, the electric generating set and the ME salt production module are sequentially connected through a steam pipeline, the high pressure boiler generates high pressure steam, the high pressure steam enters the MVR salt production module and does work to generate primary backpressure steam, the primary backpressure steam flows into the electric generating set and generates electricity to generate secondary backpressure steam, and the second backpressure steam enters the ME salt production module and participates in salt production. The invention also discloses an MVR and ME combined heat and power generation salt production technology. The system and the technology are provided to solve problems of low supplied heat grade and insufficient energy utilization of present salt production technologies, realize multi-grade utilization of steam energy, and improve the energy utilization efficiency.