The invention discloses a resin type nanoparticle latex blocking agent for drilling fluids. The blocking agent comprises raw materials in parts by weight as follows: 20 parts of alkenyl benzene, 15 parts of acrylate, 1 part of acrylates and 10 parts of hard inorganic materials, wherein the mass ratio of short-chain monomers to long-chain monomers in acrylate monomers is 3:1. The blocking agent is a composite product of the inorganic materials and organic materials, combines the hard materials with soft materials, has a higher blocking rate and is wide in particle size distribution and wider in application range; the rheological property of the drilling fluids are seldom influenced after the blocking agent is added to the drilling fluids, the blocking capacity of the drilling fluids can be remarkably improved, and the filter loss of the drilling fluids is reduced.