The invention provides a full-automatic mud removing device for radix pseudostellariae. The full-automatic mud removing device comprises a rack, wherein wheels are arranged at the two sides of the rack; a rotary drum is arranged on the rack; openings are formed in the rear end face and front end face of the rotary drum; the rear end of the rotary drum inclines downwards; the side surface of the rotary drum is hollow; a conveying belt is arranged at the front of the rotary drum; one end, far away from the rotary drum, of the conveying belt inclines downwards; one end, close to the rotary drum, of the conveying belt is arranged in the middle of the front end face of the rotary drum; rotary drum driving wheels are arranged below the rotary drum, and used for driving the rotary drum to rotate; and a sieve plate is arranged under the rear end face of the rotary drum. The conveying belt of the full-automatic mud removing device can convey radix pseudostellariae into the rotary drum, the rotary drum can carry out mud removal on radix pseudostellariae, radix pseudostellariae drops out of the rear end of the rotary drum gradually and falls onto the sieve plate, then radix pseudostellariae can be subjected to centralized collection. In this way, a full-automatic mud removal process of radix pseudostellariae is accomplished, no labor participation is required, and the manpower cost is reduced.